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XL147 analogue
SPC-02410
CAS No. 956958-53-5
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| 5 mg | Online Inquiry |
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PI3K inhibitor ; Apoptosis related activator
| Description |
|---|
| XL147 analogue (SAR245408) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ with IC50 of 39 nM/36 nM/23 nM in cell-free assays, less potent to PI3Kβ. XL147 analogue induces apoptosis. Phase 1/2. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 956958-53-5 |
| Description | XL147 analogue (SAR245408) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ with IC50 of 39 nM/36 nM/23 nM in cell-free assays, less potent to PI3Kβ. XL147 analogue induces apoptosis. Phase 1/2. |
| Formula | C21H16N6O2S2 |
| Molecular Weight | 448.52 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | SAR245408 |
| SMILES | CC1=CC=C(C=C1)S(=O)(=O)NC2=NC3=CC=CC=C3N=C2NC4=CC5=NSN=C5C=C4 |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.