WZ3146 - CD BioSciences

service-banner

WZ3146

WZ3146

SPC-02399

WZ3146

CAS No. 1214265-56-1

Size Price
10 mM (1 mL in DMSO) Online Inquiry
5 mg Online Inquiry
10 mg Online Inquiry
50 mg Online Inquiry
200 mg Online Inquiry
Bulk Size Online Inquiry

EGFR inhibitor

Description
WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM; does not inhibit ERBB2 phosphorylation (T798I).
Product Details
CAS No. CAS No. 1214265-56-1
Description WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM; does not inhibit ERBB2 phosphorylation (T798I).
Formula C24H25ClN6O2
Molecular Weight 464.95
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)OC4=CC=CC(=C4)NC(=O)C=C)Cl
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.