WP1066 - CD BioSciences

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WP1066

WP1066

SPC-02391

WP1066

CAS No. 857064-38-1

Size Price
10 mM (1 mL in DMSO) Online Inquiry
10 mg Online Inquiry
Bulk Size Online Inquiry

JAK inhibitor ; STAT inhibitor ; Apoptosis related activator

Description
WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells; shows activity to JAK2, STAT3, STAT5, and ERK1/2 not JAK1 and JAK3. WP1066 induces apoptosis. Phase 1.
Product Details
CAS No. CAS No. 857064-38-1
Description WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells; shows activity to JAK2, STAT3, STAT5, and ERK1/2 not JAK1 and JAK3. WP1066 induces apoptosis. Phase 1.
Formula C17H14BrN3O
Molecular Weight 356.22
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CC(C1=CC=CC=C1)NC(=O)C(=CC2=NC(=CC=C2)Br)C#N
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.