Online Inquiry
Wortmannin
SPC-02390
CAS No. 19545-26-7
| Size | Price |
| 5 mg | Online Inquiry |
| 10 mg | Online Inquiry |
| 20 mg | Online Inquiry |
| 100 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
PI3K inhibitor ; ATM/ATR inhibitor ; Autophagy inhibitor ; DNA-PK inhibitor ; Autophagy inhibitor ; PLK inhibitor
| Description |
|---|
| Wortmannin (KY 12420) is the first described PI3K inhibitor with IC50 of 3 nM in a cell-free assay, with little selectivity within the PI3K family. Wortmannin blocks autophagosome formation and potently inhibits DNA-PK/ATM with IC50 of 16 nM and 150 nM in cell-free assays. Wortmannin also inhibits PLK1 activity. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 19545-26-7 |
| Description | Wortmannin (KY 12420) is the first described PI3K inhibitor with IC50 of 3 nM in a cell-free assay, with little selectivity within the PI3K family. Wortmannin blocks autophagosome formation and potently inhibits DNA-PK/ATM with IC50 of 16 nM and 150 nM in cell-free assays. Wortmannin also inhibits PLK1 activity. |
| Formula | C23H24O8 |
| Molecular Weight | 428.43 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | KY 12420 |
| SMILES | CC(=O)OC1CC2(C(CCC2=O)C3=C1C4(C(OC(=O)C5=COC(=C54)C3=O)COC)C)C |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.