WHI-P154 - CD BioSciences

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WHI-P154

WHI-P154

SPC-02384

WHI-P154

CAS No. 211555-04-3

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10 mM (1 mL in DMSO) Online Inquiry
10 mg Online Inquiry
50 mg Online Inquiry
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JAK inhibitor ; EGFR inhibitor

Description
WHI-P154 is a potent JAK3 inhibitor with IC50 of 1.8 μM, no activity against JAK1 or JAK2, also inhibits EGFR, Src, Abl, VEGFR and MAPK, prevents Stat3, but not Stat5 phosphorylation.
Product Details
CAS No. CAS No. 211555-04-3
Description WHI-P154 is a potent JAK3 inhibitor with IC50 of 1.8 μM, no activity against JAK1 or JAK2, also inhibits EGFR, Src, Abl, VEGFR and MAPK, prevents Stat3, but not Stat5 phosphorylation.
Formula C16H14BrN3O3
Molecular Weight 376.2
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)O)Br)OC
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.