VX-745 - CD BioSciences

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VX-745

VX-745

SPC-02377

VX-745

CAS No. 209410-46-8

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p38 MAPK inhibitor

Description
VX-745 is a potent and selective inhibitor of p38α with IC50 of 10 nM, 22-fold greater selectivity versus p38β and no inhibition to p38γ.
Product Details
CAS No. CAS No. 209410-46-8
Description VX-745 is a potent and selective inhibitor of p38α with IC50 of 10 nM, 22-fold greater selectivity versus p38β and no inhibition to p38γ.
Formula C19H9Cl2F2N3OS
Molecular Weight 436.26
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES C1=CC(=C(C(=C1)Cl)C2=C3C=CC(=NN3C=NC2=O)SC4=C(C=C(C=C4)F)F)Cl
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.