VPS4B (-) Cell Line - CD BioSciences

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VPS4B (-) Cell Line

VPS4B (-) Cell Line

SPL-03978

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Description
VPS4B (-)
Target Information
Target Name VPS4B
Gene Abbr. VPS4B
Gene ID 9525
Full Name vacuolar protein sorting 4 homolog B
Alias MIG1, SKD1, SKD1B, VPS4-2
Species Human
Introduction The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16. [provided by RefSeq, Jul 2008].
Product Details
Cell Line Model HAP1
Genotype VPS4B (-)
Description VPS4B (-)
Parental Cell Line C631
Handling Specifications
Disclaimer This product is classified under IATA regulations as a GMMO (genetically modified micro-organism) and will ship as UN3245. If applicable, ensure facility meets all requirements per local and country regulations.

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