Vismodegib (GDC-0449) - CD BioSciences

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Vismodegib (GDC-0449)

Vismodegib (GDC-0449)

SPC-02346

Vismodegib (GDC-0449)

CAS No. 879085-55-9

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10 mM (1 mL in DMSO) Online Inquiry
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Hedgehog/Smoothened inhibitor

Description
Vismodegib (GDC-0449) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 μM in a cell-free assay.
Product Details
CAS No. CAS No. 879085-55-9
Description Vismodegib (GDC-0449) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 μM in a cell-free assay.
Formula C19H14Cl2N2O3S
Molecular Weight 421.3
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.