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Veliparib (ABT-888)
SPC-02330
CAS No. 912444-00-9
| Size | Price |
| 10 mM (1 mL in DMSO) | Online Inquiry |
| 10 mg | Online Inquiry |
| 25 mg | Online Inquiry |
| 50 mg | Online Inquiry |
| 200 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
PARP inhibitor ; Autophagy activator ; Apoptosis related activator
| Description |
|---|
| Veliparib (ABT-888, NSC 737664) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively. It is inactive to SIRT2. Veliparib increases autophagy and apoptosis. Phase 3. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 912444-00-9 |
| Description | Veliparib (ABT-888, NSC 737664) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively. It is inactive to SIRT2. Veliparib increases autophagy and apoptosis. Phase 3. |
| Formula | C13H16N4O |
| Molecular Weight | 244.29 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | NSC 737664 |
| SMILES | CC1(CCCN1)C2=NC3=C(C=CC=C3N2)C(=O)N |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.