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VEGF Receptor 3 Antibody
SPA-11747
| Size | Price |
| 0.05 mg | Online Inquiry |
| 0.1 mg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | VEGF Receptor |
| Gene Abbr. | FLT4 |
| Gene ID | 2324 |
| Full Name | fms related receptor tyrosine kinase 4 |
| Alias | CHTD7, FLT-4, FLT41, LMPH1A, LMPHM1 |
| Introduction | Vascular endothelial growth factor receptor 3 (VEGFR3) is a 195 kDa membrane receptor tyrosine kinase. VEGF receptors are characterized by the presence of seven extracellular immunoglobulin (Ig)-like domains followed by a membrane-spanning domain and a conserved intracellular tyrosine kinase domain. VEGF receptor 3 expression is largely restricted to adult lymphatic endothelium and is thought to control lymphangiogenesis. Binding of VEGF-C/VEGF-D to VEGFR3 results in transphosphorylation of tyrosine residues in its intracellular domain, recruitment of signaling molecules and activation of ERK1/2 and Akt signaling cascades. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 54733 |
| Isotype | IgG1 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human VEGF R3/Flt-4. Tyr25-Ile776. Accession # P35916. |
| Usage | |
|---|---|
| Application | FC |
| Dilutions | Flow Cytometry (10 µL/10^6 cells) |
| Reactivity | Human |
| Specificity | Detects human VEGF R3/Flt-4 in direct ELISAs. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Supplied in a saline solution containing BSA and Sodium Azide. |
| Preservative | Sodium Azide |
| Storage Temp. | Protect from light. 12 months from date of receipt, 2 to 8 °C as supplied. |
| Handling | Do not freeze. Protect from light. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.