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VEGF Receptor 1/2/3 Antibody
SPA-11731
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | VEGF Receptor |
| Gene Abbr. | FLT1 |
| Gene ID | 2321 |
| Full Name | fms related receptor tyrosine kinase 1 |
| Alias | FLT, FLT-1, VEGFR-1, VEGFR1 |
| Introduction | The vascular endothelial growth factor (VEGF) receptor (VEGFR-1, Flt-1) is a 180 kDa receptor tyrosine kinase belonging to the VEGFR (Flt) family. The receptor is comprised of seven extracellular Ig-like domains, a single transmembrane region and cytoplasmic tail containing the active kinase domain. VEGFR-1 plays an important role in endothelial cell function and normal vascular development, as well as in hematopoietic function. VEGF-A is a high affinity ligand of VEGFR-1. VEGFR-1 also binds VEGF-B and PLGF. Ligand binding results in very little VEGFR-1 kinase activation, and VEGFR-1/VEGF-A binding negatively regulates VEGF function by diverting the growth factor from other functional VEGF receptors. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 8.9106495605473E+14 |
| Isotype | IgG1 |
| Usage | |
|---|---|
| Application | FC |
| Reactivity | Human |
| Storage & Handling | |
|---|---|
| Storage Buffer | Supplied in a saline solution containing BSA and Sodium Azide. |
| Preservative | Sodium Azide |
| Storage Temp. | Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light. |
| Handling | Do not use past expiration date. Protect from light. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.