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Tyrphostin AG 1296
SPC-02291
CAS No. 146535-11-7
| Size | Price |
| 10 mM (1 mL in DMSO) | Online Inquiry |
| 5 mg | Online Inquiry |
| 25 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
PDGFR inhibitor ; c-Kit inhibitor ; FGFR inhibitor ; Apoptosis related activator
| Description |
|---|
| Tyrphostin AG 1296 is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR. Tyrphostin AG1296 inhibits FGFR and c-Kit with IC50 of 12.3 μM and 1.8 μM in Swiss 3T3 cells. Tyrphostin AG1296 induces dramatic apoptosis in A375R cells. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 146535-11-7 |
| Description | Tyrphostin AG 1296 is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR. Tyrphostin AG1296 inhibits FGFR and c-Kit with IC50 of 12.3 μM and 1.8 μM in Swiss 3T3 cells. Tyrphostin AG1296 induces dramatic apoptosis in A375R cells. |
| Formula | C16H14N2O2 |
| Molecular Weight | 266.29 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | AG 1296 |
| SMILES | COC1=C(C=C2C(=C1)N=CC(=N2)C3=CC=CC=C3)OC |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.