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Tyk2 siRNA I
SPR-01132
| Size | Price |
| 1 Unit | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | Tyk2 |
| Gene Abbr. | TYK2 |
| Gene ID | 7297 |
| Full Name | tyrosine kinase 2 |
| Alias | IMD35, JTK1 |
| Introduction | Tyk2 is a member of the Jak family of protein tyrosine kinases. It associates with and is activated by receptors for many cytokines including IL-13, the IL-6 family, IL-10, and IFN-α and β. Following ligand binding, Tyk2 is activated by phosphorylation of Tyr1054 and/or Tyr1055. Tyk2 is required for the tyrosine phosphorylation of Stat3 in the IFN-β signaling cascade. |
| Usage | |
|---|---|
| Application | RNA interference |
| Reactivity | |
| Storage & Handling | |
|---|---|
| Storage Buffer | The siRNA product is supplied in RNAse-free water. |
| Storage Temp. | Aliquot and store at -20 °C. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.