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TSLPR/CRLF2 Antibody
SPA-02404
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | CRLF2 |
| Gene Abbr. | CRLF2 |
| Gene ID | 64109 |
| Full Name | cytokine receptor like factor 2 |
| Alias | CRL2, CRLF2Y, TSLPR |
| Introduction | TSLPR is a member of the hematopoietin receptor family which acts as a receptor for the cytokine thymic stromal lymphopoietin (TSLP) that promotes CD4(+) T cell homeostasis and contributes to allergic and inflammatory responses. TSLPR is a heterodimeric complex, consisting of the IL-7R-alpha chain and a common gamma-like receptor chain. The protein contains two fibronectin type III-like domains, four conserved cysteine residues, and a WSXWS box-like motif at its N-terminal, while the C-terminal intracellular region contains box 1 and box 2-like motifs. The protein is usually expressed in liver, kidney, heart, and skeletal muscle. The gene for human TSLPR is localized to the pseudoautosomal region, Xp22.3 and Yp11.3. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 59N5G4 |
| Isotype | IgG2B Kappa |
| Immunogen | Amino acids 119-231 of human TSLPR protein were used as the immunogen for the antibody. |
| Usage | |
|---|---|
| Application | WB, IHC |
| Dilutions | Western Blot (1:100-1:2000) |
| Reactivity | Human |
| Specificity | TSLPR is a glycoprotein with two major isoforms of 359 amino acids and 255 amino acids. In Western Blotting, bands may be visualized between 27 kD and ~50 kD. |
| Storage & Handling | |
|---|---|
| Storage Buffer | 0.2 mL PBS and 0.05% BSA. |
| Preservative | 0.05% Sodium Azide |
| Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.