Triciribine - CD BioSciences

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Triciribine

Triciribine

SPC-02261

Triciribine

CAS No. 35943-35-2

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10 mM (1 mL in DMSO) Online Inquiry
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10 mg Online Inquiry
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Akt inhibitor ; DNA/RNA Synthesis inhibitor ; Anti-infection inhibitor

Description
Triciribine (NSC 154020, VD-0002, vqd-002, API-2) is a DNA synthesis inhibitor, also inhibits Akt in PC3 cell line and HIV-1 in CEM-SS, H9, H9IIIB, U1 cells with IC50 of 130 nM and 20 nM, respectively; does not inhibit PI3K/PDK1; 5000-fold less active in cells lacking adenosine kinase. Phase 1/2.
Product Details
CAS No. CAS No. 35943-35-2
Description Triciribine (NSC 154020, VD-0002, vqd-002, API-2) is a DNA synthesis inhibitor, also inhibits Akt in PC3 cell line and HIV-1 in CEM-SS, H9, H9IIIB, U1 cells with IC50 of 130 nM and 20 nM, respectively; does not inhibit PI3K/PDK1; 5000-fold less active in cells lacking adenosine kinase. Phase 1/2.
Formula C13H16N6O4
Molecular Weight 320.3
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms NSC 154020, VD-0002, vqd-002, API-2
SMILES CN1C2=NC=NC3=C2C(=CN3C4C(C(C(O4)CO)O)O)C(=N1)N
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.