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TRAF-4 Antibody
SPA-11250
Size | Price |
0.025 mL | Online Inquiry |
0.05 mL | Online Inquiry |
More Options | Online Inquiry |
Target Information | |
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Target Name | TRAF4 |
Gene Abbr. | TRAF4 |
Gene ID | 9618 |
Full Name | TNF receptor associated factor 4 |
Alias | CART1, MLN62, RNF83 |
Introduction | This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. [provided by RefSeq] |
Product Details | |
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Host | Rabbit |
Clonality | Polyclonal |
Clone No. | N/A |
Isotype | IgG |
Immunogen | This antibody was made against a protein fragment from the C Terminus Region. |
Usage | |
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Application | WB, ELISA, IHC |
Dilutions | Western Blot (1:5000-1:20000); ELISA (1:100-1:2000); Immunohistochemistry (1:10-1:500) |
Reactivity | Human |
Specificity | This product is specific for Human TRAF4. |
Storage & Handling | |
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Storage Buffer | 20 mM Potassium Phosphate (pH 7.0) and 0.15 M NaCl. |
Preservative | No Preservative |
Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.