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TPCA-1
SPC-02247
CAS No. 507475-17-4
| Size | Price |
| 10 mM (1 mL in DMSO) | Online Inquiry |
| 10 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
IκB/IKK inhibitor ; NF-κB inhibitor ; STAT inhibitor ; Apoptosis related activator
| Description |
|---|
| TPCA-1 (GW683965) is an inhibitor of IKK-2 with IC50 of 17.9 nM in a cell-free assay, inhibits NF-κB pathway, exhibits 22-fold selectivity over IKK-1. TPCA-1 is also an inhibitor of STAT3 and enhances apoptosis. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 507475-17-4 |
| Description | TPCA-1 (GW683965) is an inhibitor of IKK-2 with IC50 of 17.9 nM in a cell-free assay, inhibits NF-κB pathway, exhibits 22-fold selectivity over IKK-1. TPCA-1 is also an inhibitor of STAT3 and enhances apoptosis. |
| Formula | C12H10FN3O2S |
| Molecular Weight | 279.29 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | GW683965 |
| SMILES | C1=CC(=CC=C1C2=CC(=C(S2)NC(=O)N)C(=O)N)F |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.