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Total α-Synuclein Sandwich ELISA Kit
SPK-01166
| Size | Price |
| 1 X 96T | Online Inquiry |
| 5 X 96T | Online Inquiry |
| 10 X 96T | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | α-Synuclein |
| Gene Abbr. | Snca |
| Gene ID | 20617 |
| Full Name | synuclein, alpha |
| Alias | NACP, al, alp, alpha-Syn, alphaSYN |
| Introduction | α-Synuclein is a protein of 140-amino acids expressed abundantly in the brain. α-Synuclein is also the main component of pathogenic Lewy bodies and Lewy neurites. Research studies have shown that mutations of the α-synuclein gene are linked to Parkinson's disease.Various research studies have shown that phosphorylation of α-Synuclein at Ser129 is a highly toxic event causing degeneration of dopaminergic neurons associated with Parkinson's disease. This is proposed to occur through increased misfolding, aggregation, and accumulation of α-Synuclein phosphorylated at this site. GSK-3β is one of several kinases that has been reported to phosphorylate α-Synuclein at Ser129. |
| Product Details | |
|---|---|
| Measurement | Sandwich |
| Usage | |
|---|---|
| Application | ELISA |
| Reactivity | |
| Sensitivity | This kit detects endogenous levels of α-Synuclein protein in mouse or rat tissues. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.