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Topotecan HCl
SPC-02238
CAS No. 119413-54-6
| Size | Price |
| 10 mM (1 mL in DMSO) | Online Inquiry |
| 50 mg | Online Inquiry |
| 100 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
Topoisomerase inhibitor ; Apoptosis related activator ; Autophagy activator
| Description |
|---|
| Topotecan HCl (NSC609699, Nogitecan, SKFS 104864A) is a topoisomerase I inhibitor for MCF-7 Luc cells and DU-145 Luc cells with IC50 of 13 nM and 2 nM in cell-free assays, respectively. Topotecan HCl induces autophagy and apoptosis. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 119413-54-6 |
| Description | Topotecan HCl (NSC609699, Nogitecan, SKFS 104864A) is a topoisomerase I inhibitor for MCF-7 Luc cells and DU-145 Luc cells with IC50 of 13 nM and 2 nM in cell-free assays, respectively. Topotecan HCl induces autophagy and apoptosis. |
| Formula | C23H23N3O5.HCl |
| Molecular Weight | 457.91 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | NSC609699, Nogitecan HCl, SKFS 104864A |
| SMILES | CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC(=C5CN(C)C)O)N=C4C3=C2)O.Cl |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.