TLE1 cDNA ORF Clone, Human, C-Myc tag - CD BioSciences

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TLE1 cDNA ORF Clone, Human, C-Myc tag

TLE1 cDNA ORF Clone, Human, C-Myc tag

SPD-14701

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Description
Full length Clone DNA of Human transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) with C terminal Myc tag.
Target Information
Species Human
Target Name TLE1
Gene Abbr. TLE1
Gene ID 7088
Full Name TLE family member 1, transcriptional corepressor
Alias ESG, ESG1, GRG1
Introduction Transducin-like enhancer of split proteins (TLE1, TLE2, TLE3, TLE4, and TLE6) are mammalian homologs of Drosophila Groucho. TLEs contain several WD-repeats implicated in protein-protein interaction. TLEs are transcriptional co-repressors that bind to many transcription factors such as LEF1, Runx1, Oct-1, hepatocyte nuclear factor 3-β as well as histone H3. TLEs are differentially expressed during animal development and may have overlapping as well as distinct functions.
Product Details
Description Full length Clone DNA of Human transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) with C terminal Myc tag.
NCBI Ref Seq NM_005077.3
RefSeq ORF Size 2313 bp
Vector pCMV3-C-Myc
Promoter Enhanced CMV promoter
Tag Sequence Myc Tag Sequence: GAGCAGAAACTCATCTCAGAAGAGGATCTG
Quality Control The plasmid is confirmed by full-length sequencing.
Storage The lyophilized plasmid can be stored at ambient temperature for three months.
Usage
Sequencing Primers T7 (TAATACGACTCACTATAGGG); BGH (TAGAAGGCACAGTCGAGG);
Antibiotic in E.coli Kanamycin
Antibiotic in Mammalian cell Hygromycin
Application Stable or Transient mammalian expression
Shipping Each tube contains lyophilized plasmid.
Storage The lyophilized plasmid can be stored at ambient temperature for three months.

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