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TGR5/GPBAR1 Antibody
SPA-10708
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | TGR5/GPBAR1 |
| Gene Abbr. | GPBAR1 |
| Gene ID | 151306 |
| Full Name | G protein-coupled bile acid receptor 1 |
| Alias | BG37, GPCR19, GPR131, M-BAR, TGR5 |
| Introduction | G protein coupled bile acid receptor 1 (GPBAR1), also called M-BAR, BG37 or TGR5, is a G-protein coupled receptor superfamily member that is a widely expressed cell surface receptor for bile acids. On macrophages, bile acid engagement of GPBAR1 suppresses phagocytosis and other functions. Extracellular portions of human GPBAR1 show approximately 75% amino acid identity with corresponding regions of mouse GPBAR1. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 409522 |
| Isotype | IgG2B |
| Immunogen | NS0 mouse myeloma cell line transfected with human TGR5/GPBAR1. Met1-Asn330. Accession # Q8TDU6. |
| Usage | |
|---|---|
| Application | FC |
| Dilutions | Flow Cytometry (0.25 μg/10^6 cells) |
| Reactivity | Human |
| Specificity | Stains human TGR5/GPBAR1 transfectants but not irrelevant transfectants. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Preservative | No Preservative |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.