Human Breast Cancer Cells SK-BR3 Transfection Kit
| Kit size Volume | Quantity | ||
|---|---|---|---|
| 1.5 ml CRISPR(Cat-219446) | Inquiry | Add to cart | |
| 0.5 ml(Cat-690444) | Inquiry | Add to cart | |
| 1.5 ml(Cat-690445) | Inquiry | Add to cart | |
| 8.0 ml(Cat-703853) | Inquiry | Add to cart |
Description
Product Information
Description
SK-BR-3 is a type of breast cancer cells taken from a tumor that had spread in a 43-year-old Caucasian woman. These cells are known to contain too much of a protein called human epidermal growth factor receptor 2 (HER2/neu), which is seen in approximately 20-25% of breast cancers. SK-BR-3 cells are routinely used to study how HER2/neu affects breast cancer and to create new treatments for HER2-positive breast cancer. They are useful in studying how well drugs such as trastuzumab (Herceptin) and lapatinib (Tykerb) target the HER2 receptor. These cells are also used to study how cancer spreads and develops resistance to drugs. SK-BR-3 cells have a complex chromosomal makeup, with 34 percent of the cells having 84 chromosomes. They include microvilli, desmosomes, and glycogen granules. SK-BR-3 cells can also be used to study how certain breast cancer cells become resistant to treatment. CD BioSciences offers transfection kits for these cells.
