Ramos Kit-Human of Burkitt's lymphoma Cell
| Kit size Volume | Quantity | ||
|---|---|---|---|
| 4 ml(Cat-658321) | Inquiry | Add to cart | |
| 30 ml(Cat-658386) | Inquiry | Add to cart |
Product Information
Modes of administration
Electroporation Efficiency:Electroporation kit provides 70-85% delivery efficiency of siRNA. Electroporation efficiency was determined by RT-PCR.
Description
A 3-year-old Caucasian boy with Burkitt's lymphoma served as the patient source for the Ramos (RA 1) cell line. This cell line resembles the morphology of tumorigenic lymphoblastic tissue. The Epstein-Barr virus has not been detected in these cells. For biomedical studies on lymphatic system malignancies, these cells are helpful. These cells are frequently employed in scientific investigations to investigate the biology of lymphomas and to evaluate the effectiveness of prospective treatments. Ramos cells are known to exhibit a number of genetic abnormalities, including as the Burkitt's lymphoma-specific translocation of the c-Myc gene on chromosome 8 to the immunoglobulin heavy chain (IgH) gene on chromosome 14. These cells also exhibit significant amounts of the B-cell markers CD19 and surface immunoglobulin. Ramos cells have been utilized in a variety of investigations, including those looking into the mechanisms of neoplastic transformation, finding fresh therapeutic targets, and evaluating the effectiveness of immunotherapies.
