Human Prostate Cancer Cell PGHAM Transfection Kit

Description

PGHAM1 is a human prostate cancer cell line established from a prostate cancer patient. PGHAM1 cells are commonly used as a model system to study prostate cancer and evaluate potential therapies. Due to the resistance of pancreatic cancer to radiotherapy and chemotherapy, new therapeutic approaches are urgently needed. Preclinical studies of the PGHAM-1 cell line are helping to better understand the etiology of the disease and to discover new treatments for patients with this life-threatening disease. The PGHAM-1 cell line was derived from N-nitrosobis(2-oxopropyl)amine (BOP)-induced pancreatic tumors of Syrian hamsters (Mesocricetus auratus). The tumor showed striking similarities to human pancreatic ductal adenocarcinoma and had moderate to well-differentiated histology. PGHAM-1 contains a K-ras point mutation at codon 12, one of the most common types of K-ras mutations in human pancreatic cancer. Researchers often use PGHAM-1 in their experiments because of their rapid cell growth and high rate of metastasis. PGHAM cells are beneficial for pancreatic cancer-related biomedical research. Hamster pancreatic cancer cells of the PGHAM cell line are very similar to human pancreatic cancer cells and are therefore useful in cancer research. CD BioSciences offers a high-efficiency transfection kit for the PGHAM cell line.