Rat Adrenal Medulla Pheochromocytoma Cell PC-12 Transfection Kit
| Kit size Volume | Quantity | ||
|---|---|---|---|
| 1.5 ml CRISPR(Cat-218425) | Inquiry | Add to cart | |
| 0.5 ml(Cat-322423) | Inquiry | Add to cart | |
| 1.5 ml(Cat-323424) | Inquiry | Add to cart | |
| 8.0 ml(Cat-707426) | Inquiry | Add to cart |
Description
Product Information
Description
PC-12 cells are a popular model for studying neuronal differentiation and exocytotic release. PC-12 was originally derived from a transplantable pheochromocytoma of the rat adrenal medulla in 1976. Despite their embryological origin and similarities to neurons, PC-12 cells are not considered adult neurons. However, they can quickly differentiate into neuron-like cells when treated with nerve growth factor, which makes them useful for studying neuronal differentiation.
PC-12 cells have some limitations, such as their small size and difficulty in transfection due to limited cytoplasm. They also have a slow population doubling time of over two days and tend to form clusters in culture. Additionally, they are challenging to attach to non-coated plastic surfaces, which can make culturing them challenging.
To overcome these challenges, CD BioScience has developed a lipid-based transfection reagent optimized for the PC-12 cell line. This reagent can aid in the transfection of PC-12 cells, allowing for more efficient experimentation and study of these cells.
