Rat Myoblast Cell L6 Transfection Kit
| Kit size Volume | Quantity | ||
|---|---|---|---|
| 1.5 ml CRISPR(Cat-216512) | Inquiry | Add to cart | |
| 0.5 ml(Cat-683710) | Inquiry | Add to cart | |
| 1.5 ml(Cat-683811) | Inquiry | Add to cart | |
| 8.0 ml(Cat-705513) | Inquiry | Add to cart |
Description
Product Information
Modes of administration
Reagent exhibits at least 84% transfection efficiency of siRNA delivery. Transfection efficiency was determined by qRT-PCR.
Description
The utilization of suitable in vitro models is essential for effective research in drug discovery and therapeutic targets identification. The L6 rat myoblast cell line is one such model, demonstrating remarkable potential in this regard. Dr. Yaffe was instrumental in developing this cell line, utilizing thigh muscle tissue from Rattus norvegicus. Its structure and properties resemble those of skeletal muscle tissue, making it an optimal candidate for investigations related to muscular physiology.
Notably, the L6 cell line has been confirmed to be negative for ectromelia virus, thereby eliminating the risk of contamination by this virus. Additionally, L6 cells have demonstrated a capacity to fuse in a cell culture setting, leading to the creation of multinucleated myotubes as well as striated fibers. Furthermore, these cells exhibit high levels of cellular variability, making them an attractive option for researchers interested in studying cellular heterogeneity.
To this end, CD BioSciences has developed pre-optimized transfection reagent kits based on biodegradable polymers that effectively aid in studying the L6 rat myoblast cell line. These kits are ideal for single and multiple transfections and are an indispensable tool for exploring mammalian connective tissue.
