Human Lung Tissue Cell IRR-MRC5 Transfection Kit
Kit size Volume | Quantity | ||
---|---|---|---|
1.5 ml CRISPR(Cat-216168) | Inquiry | Add to cart | |
0.5 ml(Cat-683366) | Inquiry | Add to cart | |
1.5 ml(Cat-683467) | Inquiry | Add to cart | |
8.0 ml(Cat-705069) | Inquiry | Add to cart |
Description
Product Information
Modes of administration
Reagent exhibits at least 73% transfection efficiency of siRNA delivery. Transfection efficiency was determined by qRT-PCR.
Description
The IRR-MRC-5 cell line, harvested from the lung tissue of a 14-week-old Caucasian male fetus, is irradiated to prevent replication and division. These cells are primarily employed to feed and foster other cells, owing to their fibroblast morphology, rendering them ideal for scrutinizing human embryonic lung tissue. What's more, IRR-MRC5 cells evince stable karyotypes and low mutation rates, while they can only proliferate for a finite number of times before succumbing to replicative senescence. Given these features, scientists often leverage IRR-MRC5 cells to investigate mechanisms underlying cellular aging and senescence, encompassing changes in gene expression, telomere length, and DNA damage response pathways. Moreover, they examine the impact of genetic and environmental factors on cellular function and unearth promising therapeutic targets for sundry diseases. To further streamline research, CD BioSciences devised a lipid-based transfection reagent kit, which efficiently delivers the goods with the IRR-MRC-5 cell line.