HL-60 Electroporation Kit-Human Acute Promyelocytic Leukemia
| Kit size Volume | Quantity | ||
|---|---|---|---|
| 4 ml(Cat-175347) | Inquiry | Add to cart | |
| 30 ml(Cat-175348) | Inquiry | Add to cart |
Product Information
Modes of administration
Electroporation Efficiency:Electroporation kit provides 65-80% delivery efficiency of siRNA. Electroporation efficiency was determined by qRT-PCR.
Description
A 36-year-old female patient with acute promyelocytic leukemia (APL) provided peripheral blood tissue that was used to create the tumorigenic HL-60 cell line. This cell line has a cell type called promyeloblasts and myeloblastic cell morphology. The myc oncogene, which was derived by S.J. Collins and others, is positively expressed in these cells. HL-60 cells have been shown to spontaneously differentiate; this process can even be partially encouraged and controlled by a variety of chemicals. In scientific studies, this cell line serves as a host for transfection. The capacity of HL60 cells to differentiate into multiple types of blood cells makes them an important tool for research on hematopoiesis and blood cell formation. HL60 cells are used by researchers to look into the molecular processes behind the onset and spread of leukemia as well as to find possible treatment targets and disease biomarkers.
