Colorectal Carcinoma Cell HCT-116 Transfection Kit
| Kit size Volume | Quantity | ||
|---|---|---|---|
| 1.5 ml CRISPR(Cat-214816) | Inquiry | Add to cart | |
| 0.5 ml(Cat-681114) | Inquiry | Add to cart | |
| 1.5 ml(Cat-681215) | Inquiry | Add to cart | |
| 8.0 ml(Cat-704517) | Inquiry | Add to cart |
Description
Product Information
Modes of administration
Reagent exhibits at least 90% transfection efficiency of siRNA delivery. Transfection efficiency was determined by qRT-PCR.
Description
In research studies, the HCT116 cell line is widely used to investigate human colorectal carcinoma. The cells were isolated from the colon of a 44-year-old male back in 1982, and since then, have been extensively characterized due to their ability to form tumors in vivo. As a result, they are frequently employed for exploring cancer biology and testing anti-cancer medications. The HCT116 cell line is diploid and lacks the mismatch repair gene MLH1, rendering it a valuable model for examining the genetic underpinnings of colorectal cancer. These cells are adherent and readily grow in culture, tolerating diverse media and conditions. HCT116 cells have been extensively used in studying numerous aspects of cancer biology, such as DNA repair mechanisms, cell cycle regulation, apoptosis, and drug resistance. CD BioSciences provides high-efficiency transfection reagent kits specifically optimized for the HCT-116 cell line.
