Pancreas Tumor Beta-TC-6 Transfection Kit

Description

Diabetes is a disease in which the body does not use enough insulin or produce enough insulin, resulting in high blood sugar. Insulinoma is a rare, neuroendocrine tumor that forms in the islet cells of the pancreas. The rarity of insulinoma presents a challenge for the development of novel therapeutics that can address it. Transfection studies on cancer cell lines in vitro are a reliable and widely accepted method for preclinical research. The Beta-TC-6 cell line was established from pancreatic tumor tissue of insulinoma-bearing transgenic mice (Mus musculus). These cells are transgenic for the SV40 large T antigen and exhibit an epithelial morphology (beta cell type). They are known to produce glucagon, insulin and somatostatin, but primarily secrete insulin in response to the presence of glucose. Beta-TC-6 cells benefit biomedical research related to diabetes. In order to facilitate in-depth research, a specific and efficient cell transfection system is essential. To this end, CD BioSciences has developed a specific transfection kit for the Beta-TC-6 cell line.