Mouse Triple-Negative Breast Cancer Cell 4T1 Transfection Kit
Kit size Volume | Quantity | ||
---|---|---|---|
0.5 ml(Cat-116343) | Inquiry | Add to cart | |
1.5 ml(Cat-116344) | Inquiry | Add to cart | |
1.5 ml CRISPR(Cat-220345) | Inquiry | Add to cart | |
8.0 ml(Cat-701346) | Inquiry | Add to cart |
Description
Product Information
Description
A rare form of breast cancer called triple-negative breast cancer lacks estrogen, progesterone, or HER2 receptors. It is an aggressive form of cancer with few curative options. The mammary gland tumor of a mouse (Mus musculus) was used to create the 4T1 triple-negative cell line. Without using any mutagens, this cell line was chosen for its 6-thioguanine resistance. This kind of tumor affects mice and spreads swiftly and easily throughout their bodies. This tumor-producing cell line displays cellular morphology that is epithelial. These cells serve as an effective cancer research model. As a result of its tumor's resemblance to human breast cancer and ease with which it spreads through mice, the 4T1 cell line is particularly useful for investigations on stage IV human breast cancer. The 4T1 mouse breast cancer cell line can mimic the aggressive phenotype of human breast cancer and is transplantable. For the 4T1 cell line, CD BioSciences provides pre-optimized transfection kits.