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TDAG8/GPR65 Antibody
SPA-04755
| Size | Price |
| 100 µg | Online Inquiry |
| 25 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | GPR65 |
| Gene Abbr. | GPR65 |
| Gene ID | 8477 |
| Full Name | G protein-coupled receptor 65 |
| Alias | TDAG8, hTDAG8 |
| Introduction | Human G Protein-Coupled Receptor 65 (GPR65), also known as T-Cell Death-Associated Gene 8 Protein (TDAG8) and Psychosine Receptor, is a 337 aminoacids proton-sensing GPCR primarily expressed in lymphoid tissues and is uniquely expressed in Th17 cells; mice deficient in GPR65 are resistant to autoimmunity. GPR65 senses pH by protonation of histidine residues on its extracellular domain. Many pH-sensing G protein-coupled receptors have emerged as potential therapeutic agents in conditions that involve the response to acidotic stress. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | 976128 |
| Isotype | IgG2B |
| Immunogen | NS0 mouse myeloma cell line transfected with human TDAG8/GPR65. Met1-Glu337. Accession # Q81IYL9. |
| Usage | |
|---|---|
| Application | WB, IF |
| Dilutions | Western Blot (2 µg/mL); Immunofluorescence (8-25 µg/mL) |
| Reactivity | Human |
| Specificity | Detects human TDAG8/GPR65 in direct ELISAs. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.