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TAO Kinase 1 Antibody
SPA-10582
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | TAO Kinase |
| Gene Abbr. | TAOK1 |
| Gene ID | 57551 |
| Full Name | TAO kinase 1 |
| Alias | KFC-B, MAP3K16, MARKK, PSK-2, PSK2 |
| Introduction | TAOK1, a member of the Ste20 kinase family, is a TAO type protein kinase that acts as an upstream activator to MARK by phosphorylation. When activated, MARK enhances microtubule dynamics and leads to phosphorylation and detachment of tau or equivalent MAPs from microtubules. Overexpression of MARK eventually leads to microtubule breakdown and cell death, but in neuronal cells the primary effect is to allow the development of neurites during differentiation. |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | TAO11.2 |
| Isotype | IgG2A Kappa |
| Immunogen | His-tagged recombinant human TAO1 (722-1001) generated in E.coli. |
| Usage | |
|---|---|
| Application | WB, IF |
| Dilutions | Western Blot (1:100-1:2000); Immunofluorescence (1:10-1:500) |
| Reactivity | Human |
| Validation | Knockdown Validated. |
| Storage & Handling | |
|---|---|
| Storage Buffer | PBS. |
| Preservative | 0.02% Sodium Azide |
| Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.