Talazoparib (BMN 673) - CD BioSciences

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Talazoparib (BMN 673)

Talazoparib (BMN 673)

SPC-02130

Talazoparib (BMN 673)

CAS No. 1207456-01-6

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PARP inhibitor

Description
Talazoparib (BMN 673) is a novel PARP inhibitor with IC50 of 0.57 nM for PARP1 in a cell-free assay. It is also a potent inhibitor of PARP-2, but does not inhibit PARG and is highly sensitive to PTEN mutation. Phase 3.
Product Details
CAS No. CAS No. 1207456-01-6
Description Talazoparib (BMN 673) is a novel PARP inhibitor with IC50 of 0.57 nM for PARP1 in a cell-free assay. It is also a potent inhibitor of PARP-2, but does not inhibit PARG and is highly sensitive to PTEN mutation. Phase 3.
Formula C19H14F2N6O
Molecular Weight 380.35
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms LT-673
SMILES CN1C(=NC=N1)C2C(NC3=CC(=CC4=C3C2=NNC4=O)F)C5=CC=C(C=C5)F
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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