SPTAN1 Sandwich ELISA Kit - CD BioSciences

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SPTAN1 Sandwich ELISA Kit

SPTAN1 Sandwich ELISA Kit

SPK-01165

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Target Information
Target Name α-Fodrin
Gene Abbr. SPTAN1
Gene ID 6709
Full Name spectrin alpha, non-erythrocytic 1
Alias DEE5, EIEE5, NEAS, SPTA2
Introduction Fodrin (also named nonerythroid spectrin) is a universally expressed membrane-associated cytoskeletal protein consisting of alpha- and beta-subunits. This protein is important for maintaining normal membrane structure and supporting cell surface protein function. Alpha-fodrin is one of the primary targets cleaved by caspases during apoptosis. The full length 240 kDa protein can be cleaved at several sites within its sequence by activated caspases to yield amino-terminal 150 kDa, carboxy-terminal 120 kDa and 35 kDa major products. Cleavage of alpha-fodrin leads to membrane malfunction and cell shrinkage.
Product Details
Measurement Sandwich
Usage
Application ELISA
Reactivity
Assay Principle quantitative
Sensitivity 0.078 ng/mL
Detection Range 0.312 ng/mL - 20 ng/mL
Sample Volume 50-100μL
Assay Time 1-5h
Detection Wavelength 450 nm
Precision Intra-assay Precision (Precision within an assay): CV%<8%.
Inter-assay Precision (Precision between assays): CV%<10%.
Storage & Handling
Storage Temp. Store at 2-8°C. Please refer to protocol.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.