Serabelisib (TAK-117) - CD BioSciences

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Serabelisib (TAK-117)

Serabelisib (TAK-117)

SPC-02005

Serabelisib (TAK-117)

CAS No. 1268454-23-4

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PI3K inhibitor

Description
Serabelisib (INK-1117,MLN-1117,TAK-117) is a potent and selective oral PI3Kα isoform inhibitor (IC50 of 21 nmol/L against PI3Kα) that has demonstrated > 100-fold selectivity relative to other class I PI3K family members (PI3Kβ/γ/δ) and mTOR, and a high degree of selectivity against many other kinase.
Product Details
CAS No. CAS No. 1268454-23-4
Description Serabelisib (INK-1117,MLN-1117,TAK-117) is a potent and selective oral PI3Kα isoform inhibitor (IC50 of 21 nmol/L against PI3Kα) that has demonstrated > 100-fold selectivity relative to other class I PI3K family members (PI3Kβ/γ/δ) and mTOR, and a high degree of selectivity against many other kinase.
Formula C19H17N5O3
Molecular Weight 363.37
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms INK-1117,MLN-1117
SMILES C1COCCN1C(=O)C2=CN=C3N2C=C(C=C3)C4=CC5=C(C=C4)OC(=N5)N
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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