Semaxanib (SU5416) - CD BioSciences

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Semaxanib (SU5416)

Semaxanib (SU5416)

SPC-02000

Semaxanib (SU5416)

CAS No. 194413-58-6; 204005-46-9

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VEGFR inhibitor

Description
Semaxanib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor with IC50 of 1.23 μM, 20-fold more selective for VEGFR than PDGFRβ, lack of activity against EGFR, InsR and FGFR. Phase 3.
Product Details
CAS No. CAS No. 194413-58-6; 204005-46-9
Description Semaxanib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor with IC50 of 1.23 μM, 20-fold more selective for VEGFR than PDGFRβ, lack of activity against EGFR, InsR and FGFR. Phase 3.
Formula C15H14N2O
Molecular Weight 238.28
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CC1=CC(=C(N1)C=C2C3=CC=CC=C3NC2=O)C
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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