Selisistat (EX 527) - CD BioSciences

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Selisistat (EX 527)

Selisistat (EX 527)

SPC-01996

Selisistat (EX 527)

CAS No. 49843-98-3

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Sirtuin inhibitor

Description
Selisistat (EX 527, SEN0014196) is a potent and selective SIRT1 inhibitor with IC50 of 38 nM in a cell-free assay, exhibits >200-fold selectivity against SIRT2 and SIRT3. Phase 2.
Product Details
CAS No. CAS No. 49843-98-3
Description Selisistat (EX 527, SEN0014196) is a potent and selective SIRT1 inhibitor with IC50 of 38 nM in a cell-free assay, exhibits >200-fold selectivity against SIRT2 and SIRT3. Phase 2.
Formula C13H13ClN2O
Molecular Weight 248.71
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms SEN0014196
SMILES C1CC(C2=C(C1)C3=C(N2)C=CC(=C3)Cl)C(=O)N
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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