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SB202190 (FHPI)
SPC-01958
CAS No. 152121-30-7
| Size | Price |
| 10 mM (1 mL in DMSO) | Online Inquiry |
| 25 mg | Online Inquiry |
| 200 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
p38 MAPK inhibitor ; Autophagy activator ; Apoptosis related inhibitor ; Ferroptosis inhibitor
| Description |
|---|
| SB202190 (FHPI) is a potent p38 MAPK inhibitor targeting p38α/β with IC50 of 50 nM/100 nM in cell-free assays, sometimes used instead of SB 203580 to investigate potential roles for SAPK2a/p38 in vivo. SB202190 inhibits endothelial cell apoptosis via induction of autophagy and heme oxygenase-1. SB202190 significantly suppresses Erastin‐dependent ferroptosis. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 152121-30-7 |
| Description | SB202190 (FHPI) is a potent p38 MAPK inhibitor targeting p38α/β with IC50 of 50 nM/100 nM in cell-free assays, sometimes used instead of SB 203580 to investigate potential roles for SAPK2a/p38 in vivo. SB202190 inhibits endothelial cell apoptosis via induction of autophagy and heme oxygenase-1. SB202190 significantly suppresses Erastin‐dependent ferroptosis. |
| Formula | C20H14N3OF |
| Molecular Weight | 331.34 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | N/A |
| SMILES | C1=CC(=CC=C1C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F)O |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.