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Rosiglitazone maleate
SPC-01901
CAS No. 155141-29-0
| Size | Price |
| 10 mM (1 mL in DMSO) | Online Inquiry |
| 25 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
PPAR agonist ; TRP Channel modulator ; Autophagy activator ; Ferroptosis inhibitor
| Description |
|---|
| Rosiglitazone maleate (BRL 49653), a member of the thiazolidinedione class of antihyperglycaemic agents, is a high-affinity selective agonist of the peroxisome proliferator-activated receptor-γ (PPAR-γ) with IC50 of 42 nM. Rosiglitazone maleate also modulates TRP channels and induces autophagy. Rosiglitazone prevents ferroptosis. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 155141-29-0 |
| Description | Rosiglitazone maleate (BRL 49653), a member of the thiazolidinedione class of antihyperglycaemic agents, is a high-affinity selective agonist of the peroxisome proliferator-activated receptor-γ (PPAR-γ) with IC50 of 42 nM. Rosiglitazone maleate also modulates TRP channels and induces autophagy. Rosiglitazone prevents ferroptosis. |
| Formula | C18H19N3O3S.C4H4O4 |
| Molecular Weight | 473.5 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | BRL 49653 |
| SMILES | CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3.C(=CC(=O)O)C(=O)O |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.