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Rocaglamide
SPC-01890
CAS No. 84573-16-0
| Size | Price |
| 1 mg | Online Inquiry |
| 5 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
eIF4A inhibitor; NF-κB activator; HSF1 activator
| Description |
|---|
| Rocaglamide is a potent inhibitor of NF-κB activation and heat shock factor 1 (HSF1) activation with IC50 of ~50 nM for HSF1. Rocaglamide inhibits thetranslation initiation factor eIF4A with anticancer properties in leukemia. Rocaglamide is isolated from the genus Aglaia and can be used for coughs, injuries, asthma and inflammatory skin diseases. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 84573-16-0 |
| Description | Rocaglamide is a potent inhibitor of NF-κB activation and heat shock factor 1 (HSF1) activation with IC50 of ~50 nM for HSF1. Rocaglamide inhibits thetranslation initiation factor eIF4A with anticancer properties in leukemia. Rocaglamide is isolated from the genus Aglaia and can be used for coughs, injuries, asthma and inflammatory skin diseases. |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | Roc-A |
| SMILES | CN(C)C(=O)C1C(C2(C(C1O)(C3=C(O2)C=C(C=C3OC)OC)O)C4=CC=C(C=C4)OC)C5=CC=CC=C5 In vivo Formulation Calculator (Clear solution) |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.