RO5126766 (CH5126766) - CD BioSciences

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RO5126766 (CH5126766)

RO5126766 (CH5126766)

SPC-01888

RO5126766 (CH5126766)

CAS No. 946128-88-7

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Raf inhibitor ; MEK inhibitor

Description
RO5126766 (CH5126766) is a dual RAF/MEK inhibitor with IC50 of 8.2 nM,19 nM, 56 nM, and 160 nM for BRAF V600E, BRAF, CRAF, and MEK1, respectively. Phase 1.
Product Details
CAS No. CAS No. 946128-88-7
Description RO5126766 (CH5126766) is a dual RAF/MEK inhibitor with IC50 of 8.2 nM,19 nM, 56 nM, and 160 nM for BRAF V600E, BRAF, CRAF, and MEK1, respectively. Phase 1.
Formula C21H18FN5O5S
Molecular Weight 471.46
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CC1=C(C(=O)OC2=C1C=CC(=C2)OC3=NC=CC=N3)CC4=C(C(=NC=C4)NS(=O)(=O)NC)F
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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