Resatorvid (TAK-242) - CD BioSciences

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Resatorvid (TAK-242)

Resatorvid (TAK-242)

SPC-01855

Resatorvid (TAK-242)

CAS No. 243984-11-4

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TLR inhibitor ; TNF-alpha inhibitor ; Autophagy inhibitor ; Interleukins inhibitor

Description
Resatorvid (TAK-242) is a small-molecule-specific inhibitor of Toll-like receptor (TLR) 4 signaling, blocking LPS-induced production of NO, TNF-α, IL-6, and IL-1β in macrophages with IC50 values of 1-11 nM. Resatorvid inhibits autophagy.
Product Details
CAS No. CAS No. 243984-11-4
Description Resatorvid (TAK-242) is a small-molecule-specific inhibitor of Toll-like receptor (TLR) 4 signaling, blocking LPS-induced production of NO, TNF-α, IL-6, and IL-1β in macrophages with IC50 values of 1-11 nM. Resatorvid inhibits autophagy.
Formula C15H17ClFNO4S
Molecular Weight 361.82
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CCOC(=O)C1=CCCCC1S(=O)(=O)NC2=C(C=C(C=C2)F)Cl
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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