Repotrectinib (TPX-0005) - CD BioSciences

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Repotrectinib (TPX-0005)

Repotrectinib (TPX-0005)

SPC-01853

Repotrectinib (TPX-0005)

CAS No. 1802220-02-5

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ALK inhibitor ; Src inhibitor ; ROS1 inhibitor ; Trk receptor inhibitor

Description
Repotrectinib (TPX-0005) is a novel ALK/ROS1/TRK inhibitor with the IC50 values of 1.01 nM for WT ALK, 1.26 nM for ALK(G1202R), and 1.08 nM for ALK(L1196M); also a potent SRC inhibitor (IC50 5.3 nM).
Product Details
CAS No. CAS No. 1802220-02-5
Description Repotrectinib (TPX-0005) is a novel ALK/ROS1/TRK inhibitor with the IC50 values of 1.01 nM for WT ALK, 1.26 nM for ALK(G1202R), and 1.08 nM for ALK(L1196M); also a potent SRC inhibitor (IC50 5.3 nM).
Formula C18H18FN5O2
Molecular Weight 355.37
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CC1CNC(=O)C2=C3N=C(C=CN3N=C2)NC(C4=C(O1)C=CC(=C4)F)C
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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