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Repotrectinib (TPX-0005)
SPC-01853
CAS No. 1802220-02-5
Size | Price |
5 mg | Online Inquiry |
25 mg | Online Inquiry |
100 mg | Online Inquiry |
Bulk Size | Online Inquiry |
ALK inhibitor ; Src inhibitor ; ROS1 inhibitor ; Trk receptor inhibitor
Description |
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Repotrectinib (TPX-0005) is a novel ALK/ROS1/TRK inhibitor with the IC50 values of 1.01 nM for WT ALK, 1.26 nM for ALK(G1202R), and 1.08 nM for ALK(L1196M); also a potent SRC inhibitor (IC50 5.3 nM). |
Product Details | |
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CAS No. | CAS No. 1802220-02-5 |
Description | Repotrectinib (TPX-0005) is a novel ALK/ROS1/TRK inhibitor with the IC50 values of 1.01 nM for WT ALK, 1.26 nM for ALK(G1202R), and 1.08 nM for ALK(L1196M); also a potent SRC inhibitor (IC50 5.3 nM). |
Formula | C18H18FN5O2 |
Molecular Weight | 355.37 |
Storage | 3 years -20°C powder 2 years -80°C in solvent |
Synonyms | N/A |
SMILES | CC1CNC(=O)C2=C3N=C(C=CN3N=C2)NC(C4=C(O1)C=CC(=C4)F)C |
Usage | |
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Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.