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Regorafenib Monohydrate
SPC-01850
CAS No. 1019206-88-2
| Size | Price |
| 25 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
VEGFR inhibitor ; PDGFR inhibitor ; c-Kit inhibitor ; c-RET inhibitor ; Raf inhibitor
| Description |
|---|
| Regorafenib (BAY-734506, fluoro-sorafenib, Resihance, Stivarga) Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-β, KIT, RET, RAF-1, B-RAF and B-RAF(V600E) respectively. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 1019206-88-2 |
| Description | Regorafenib (BAY-734506, fluoro-sorafenib, Resihance, Stivarga) Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-β, KIT, RET, RAF-1, B-RAF and B-RAF(V600E) respectively. |
| Formula | C21H15ClF4N4O3.H2O |
| Molecular Weight | 500.83 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | BAY-734506, fluoro-sorafenib, Resihance, Stivarga |
| SMILES | CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F.O |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.