Refametinib (RDEA119) - CD BioSciences

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Refametinib (RDEA119)

Refametinib (RDEA119)

SPC-01848

Refametinib (RDEA119)

CAS No. 923032-37-5

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MEK inhibitor

Description
Refametinib (RDEA119, Bay 86-9766) is a potent, ATP non-competitive and highly selective inhibitor of MEK1 and MEK2 with IC50 of 19 nM and 47 nM, respectively.
Product Details
CAS No. CAS No. 923032-37-5
Description Refametinib (RDEA119, Bay 86-9766) is a potent, ATP non-competitive and highly selective inhibitor of MEK1 and MEK2 with IC50 of 19 nM and 47 nM, respectively.
Formula C19H20F3IN2O5S
Molecular Weight 572.34
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms Bay 86-9766
SMILES COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)CC(CO)O)NC3=C(C=C(C=C3)I)F)F)F
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.