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REDD1 Antibody
SPA-09544
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | REDD1 |
| Gene Abbr. | DDIT4 |
| Gene ID | 54541 |
| Full Name | DNA damage inducible transcript 4 |
| Alias | Dig2, REDD-1, REDD1 |
| Introduction | REDD1 (REgulated in Development and DNA damage responses) expression is induced by hypoxia, cell stress, apoptosis and DNA damage. REDD1 is a transcriptional target of p53 and p63 following DNA damage, and links p63 to Ros. REDD1 functions as a negative regulator of mTOR in response to hypoxia in a tuberin-dependent manner. Depending on cell context, REDD1 can either be protecting or detrimental for cells under oxidative or ischemic stresses. |
| Product Details | |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Immunogen | Synthetic peptide surrounding Asn60 of human REDD1. |
| Source/Purification | Antibodies are produced by immunizing animals with a synthetic peptide surrounding Asn60 of human REDD1. Antibodies are purified by peptide affinity chromatography. |
| Usage | |
|---|---|
| Application | WB |
| Dilutions | Western Blot (1:1000) |
| MW(KDa) | 28 |
| Reactivity | Human |
| Sensitivity | Transfected Only |
| Specificity | It detects transfected levels of REDD1 protein. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA and 50% glycerol. |
| Preservative | No Preservative |
| Storage Temp. | Store at -20 °C. |
| Handling | Do not aliquot the antibody. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.