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Recombinant Rat Vang-like protein 2 (Vangl2)
SPP-05292
| Size | Price |
| 20 μg | Online Inquiry |
| 100 μg | Online Inquiry |
| Target Information | |
|---|---|
| Species | Rattus norvegicus |
| Target Name | VANGL2 |
| UniProt No. | P84889 |
| Subcellular Location | Cell membrane, Multi-pass membrane protein |
| Tissue Specificity | Asymmetrically localized to specific cell-cell boundaries in the developing inner ear. |
| Gene Abbr. | Vangl2 |
| Full Name | VANGL planar cell polarity protein 2 |
| Alias | Ltap |
| Introduction | Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity). |
| Product Details | |
|---|---|
| Product Type | Recombinant Protein |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
| Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.