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Recombinant Rat Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform (Ppp2r2b)
SPP-04341
| Size | Price |
| 20 μg | Online Inquiry |
| 100 μg | Online Inquiry |
| 500 μg | Online Inquiry |
| Target Information | |
|---|---|
| Species | Rattus norvegicus |
| Target Name | PPP2R2B |
| UniProt No. | P36877 |
| Subcellular Location | Isoform 1: Cytoplasm, Cytoplasm, cytoskeleton, Membrane; Isoform 2: Cytoplasm, Mitochondrion, Mitochondrion outer membrane |
| Tissue Specificity | Expressed in the brain. Isoform 1 and isoform 2 are expressed in the forbrain. Isoform 1 is more strongly expressed than isoform 2 in the olfactory bulb. Isoform 1 and isoform 2 are weakly expressed in the cerebellum. Isoform 1 is expressed in the testis. |
| Gene Abbr. | Ppp2r2b |
| Full Name | protein phosphatase 2, regulatory subunit B, beta |
| Alias | Pppr2b2 |
| Introduction | The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity. Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance. |
| Product Details | |
|---|---|
| Product Type | Recombinant Protein |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
| Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.