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Recombinant Rat Platelet-derived growth factor D (Pdgfd)
SPP-04139
Size | Price |
20 μg | Online Inquiry |
100 μg | Online Inquiry |
500 μg | Online Inquiry |
Target Information | |
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Species | Rattus norvegicus |
Target Name | PDGFD |
UniProt No. | Q9EQT1 |
Subcellular Location | Secreted |
Tissue Specificity | Widely expressed. Expressed at high levels in the kidney, adrenal glands, eye and CNS. In the kidney the localization is confined to arterial and arteriolar vascular smooth muscle cells and is also detected at low levels in the glomeruli In the eye. |
Gene Abbr. | Pdgfd |
Full Name | platelet derived growth factor D |
Alias | Scdgfb, rSCDGF-B |
Introduction | Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis (By similarity). May play an important role in control of lens epithelial cell proliferation. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix. |
Product Details | |
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Product Type | Recombinant Protein |
Storage & Handling | |
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Storage Temp. | Store at -20 °C upon receipt unless otherwise instructed. |
Handling | Aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.